R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin

  • Applicable to Systemic inflammatory response syndrome (SIRS) of non-infectious origin
  • The 2025 edition of ICD10-CM R65.1 became effective on October 1, 2024.
  • This is the American ICD10-CM version of R65.1 - other international versions of ICD10 R65.1 may differ.
  • R65.1 is a Non-Billable / Non-Specific ICD10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • R65.1 Code should not be used for billing or reimbursement purposes as there are multiple ICD-10 CM codes below it that contain a greater level of detail.
  • R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin
    • R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin
    • R65.10 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
    • R65.11 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

Type 1 Excludes

  • sepsis- code to infection
  • severe sepsis (R65.2)

codefirst

  • underlying condition, such as:
  • heatstroke (T67.0-)
  • injury and trauma (S00-T88)

The following codes above R65.1 contain annotation back-references that may be applicable to R65.1:

Chapter: R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Section: R50-R69 General symptoms and signs

Category: R65 Symptoms and signs specifically associated with systemic inflammation and infection

     
Non-Billable/Non-Specific Code

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