D68.5 - Primary thrombophilia

  • Applicable to Primary thrombophilia
  • The 2025 edition of ICD10-CM D68.5 became effective on October 1, 2024.
  • This is the American ICD10-CM version of D68.5 - other international versions of ICD10 D68.5 may differ.
  • D68.5 is a Non-Billable / Non-Specific ICD10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • D68.5 Code should not be used for billing or reimbursement purposes as there are multiple ICD-10 CM codes below it that contain a greater level of detail.
  • D68.5 - Primary thrombophilia
    • D68.5 - Primary thrombophilia
    • D68.51 - Activated protein C resistance
    • D68.52 - Prothrombin gene mutation
    • D68.59 - Other primary thrombophilia

 Inclusion Term

  • Primary hypercoagulable states

Type 1 Excludes

  • antiphospholipid syndrome (D68.61)
  • lupus anticoagulant (D68.62)
  • secondary activated protein C resistance (D68.69)
  • secondary antiphospholipid antibody syndrome (D68.69)
  • secondary lupus anticoagulant with hypercoagulable state (D68.69)
  • secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
  • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  • systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
  • thrombotic thrombocytopenic purpura (M31.19)

The following codes above D68.5 contain annotation back-references that may be applicable to D68.5:

Chapter: D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Section: D65-D69 Coagulation defects, purpura and other hemorrhagic conditions

Category: D68 Other coagulation defects

  
Non-Billable/Non-Specific Code

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