D89.83 - Cytokine release syndrome

Applicable to Cytokine release syndrome
The 2025 edition of ICD10-CM D89.83 became effective on October 1, 2024.
This is the American ICD10-CM version of D89.83 - other international versions of ICD10 D89.83 may differ.
D89.83 is a Non-Billable / Non-Specific ICD10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
D89.83 Code should not be used for billing or reimbursement purposes as there are multiple ICD-10 CM codes below it that contain a greater level of detail.

D89.83 - Cytokine release syndrome
- D89.83 - Cytokine release syndrome
- D89.831 - Cytokine release syndrome, grade 1
- D89.832 - Cytokine release syndrome, grade 2
- D89.833 - Cytokine release syndrome, grade 3
- D89.834 - Cytokine release syndrome, grade 4
- D89.835 - Cytokine release syndrome, grade 5
- D89.839 - Cytokine release syndrome, grade unspecified

Code Additional Code

code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

codefirst

underlying cause, such as:
complications following infusion, transfusion and therapeutic injection (T80.89-)
complications of transplanted organs and tissue (T86.-)

The following codes above D89.83 contain annotation back-references that may be applicable to D89.83:

Chapter: D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Section: D80-D89 Certain disorders involving the immune mechanism

Category: D89 Other disorders involving the immune mechanism, not elsewhere classified

cytokine icd 10

syndrome icd 10

Non-Billable/Non-Specific Code

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Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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