2025 HCPCS Code G0481
Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performed
TAGS: individual utilizing samples matrix method tandem necessarily internal quality variations instrument specimen identification drugs recognized single enzymatic identify standards immunoassays isomers universally qualitative performed interferences distinguish alcohol calibration isotope methods signal excluding validity limited material control structural stable spectral| Short Description | Drug test def 8-14 classes |
| HCPCS Action Code | N - No maintenance for this code |
| HCPCS Coverage Code | C - Carrier judgment |
| HCPCS Code Added Date | January 01, 2016 |
| HCPCS Action Effective Date | January 01, 2017 |
| HCPCS Pricing Indicator Code | 21 - Price subject to national limitation amount |
| HCPCS Type Of Service Code | 5 - Diagnostic laboratory |
| HCPCS Multiple Pricing Indicator Code | A - Not applicable as HCPCS priced under one methodology |
| HCPCS Anesthesia Base Unit Quantity | 0 |
| HCPCS Coverage Issues Manual Reference Section Number | 340 - Toxicology - - - |
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